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ZIRC
ZFIN ID: ZDB-GENE-030131-7118
Gene Name: vasodilator stimulated phosphoprotein b
Gene Symbol: vaspb    Nomenclature History

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Previous Names: vasp, si:ch211-202c21.1, si:dkey-113g17.1, wu:fb23b04, wu:fk84g05, zgc:110347

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have SH3 domain binding activity and profilin binding activity. Predicted to be involved in actin cytoskeleton organization; nervous system development; and positive regulation of actin filament polymerization. Is expressed in several structures, including apical ectodermal ridge pectoral fin bud; epidermis; pectoral fin; pharyngeal arch; and solid lens vesicle. Orthologous to human VASP (vasodilator stimulated phosphoprotein).
Genome Resources: Alliance (1),  Gene:550487 (1),  Ensembl(GRCz11):ENSDARG00000017105 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [MGC:110347]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15540 Point Mutation Unknown Missense, Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16008 Point Mutation Unknown Splice Site, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23365 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vaspb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vaspb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin polymerization or depolymerization (more)
    Molecular Function profilin binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vaspb-201 (1)    Ensembl 2964
    vaspb-202 (1)    Ensembl 1413
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vaspb No data available
    MARKER RELATIONSHIPS
    vaspb Contained in: [BAC] CH73-76G6 (1) (order this), CH211-202C21 (1) (order this), DKEY-113G17 (1) (order this)
    vaspb Encodes: [EST] fb23b04 (1), fk84g05
    [cDNA] MGC:110347 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005173679 (1)
    Genomic GenBank:AL928979 (1) 193205 bp
    Select Tool
    Polypeptide UniProtKB:Q1LVK6 (1) 445 aa
    Sequence Clusters UniGene:106500 (1)
    Sequence Information (all 43)
    ORTHOLOGY for vaspb ( Chr: 18 )
    CITATIONS (27)