ZFIN ID: ZDB-GENE-030131-7074
Gene Name: hes related family bHLH transcription factor with YRPW motif like
Gene Symbol: heyl    Nomenclature History

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Previous Names: fk74e12, wu:fk74e12 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including Notch signaling pathway; negative regulation of transcription by RNA polymerase II; and regulation of neurogenesis. Predicted to localize to nucleus. Is expressed in epidermis; nervous system; neural rod; neural tube; and tail bud. Orthologous to human HEYL (hes related family bHLH transcription factor with YRPW motif like).
Genome Resources: Alliance (1),  Gene:335134 (1),  Ensembl(GRCz11):ENSDARG00000055798 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa44920 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH heyl HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH heyl VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA heyl-201 (1)    Ensembl 1619
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM heyl No data available
    MARKER RELATIONSHIPS
    heyl Contained in: [BAC] DKEY-148N22 (1) (order this)
    heyl Encodes: [EST] eu2 (1), fk74e12
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_181736 (1) 1620 nt
    Genomic GenBank:CR318628 (1) 115655 nt
    Select Tool
    Polypeptide UniProtKB:Q8AXV5 (1) 310 aa
    Sequence Information (all 10)
    ORTHOLOGY for heyl ( Chr: 19 )
    CITATIONS (28)