ZFIN ID: ZDB-GENE-030131-7031
Gene Name: cAMP responsive element modulator a
Gene Symbol: crema    Nomenclature History

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Previous Names: Zfcrem (1), fk66d05, si:dkey-177e13.4 (1), wu:fk66d05

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to the transcription factor complex. Is expressed in brain. Orthologous to human CREM (cAMP responsive element modulator).
Genome Resources: Alliance (1),  Gene:555432 (1),  Ensembl(GRCz11):ENSDARG00000023217 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8779 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH crema HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH crema VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001630 cAMP response element binding (CREB) protein
    Domain IPR003102 Coactivator CBP, pKID
    Domain IPR004827 Basic-leucine zipper domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA crema-202 (1)    Ensembl 1089
    crema-203 (1)    Ensembl 907
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM crema No data available
    MARKER RELATIONSHIPS
    crema Contained in: [BAC] CH211-212E22 (1), DKEY-177E13 (1) (order this)
    crema Encodes: [EST] fk66d05
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005171403 (1) 5313 bp
    Genomic GenBank:BX088693 (1) 150021 bp
    Select Tool
    Polypeptide UniProtKB:E7F9I0 (1) 300 aa
    Sequence Information (all 20)
    ORTHOLOGY for crema ( Chr: 2 )
    CITATIONS (18)