ZFIN ID: ZDB-GENE-030131-6986
Gene Name: nucleolin
Gene Symbol: ncl    Nomenclature History

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Previous Names: fa12d03, wu:fa12d03, zgc:152810

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have mRNA binding activity. Involved in heart looping; rRNA processing; and rRNA transcription. Predicted to localize to cytoplasm; nucleus; and ribonucleoprotein complex. Is expressed in cardiac ventricle. Orthologous to human NCL (nucleolin).
Genome Resources: Alliance (1),  Gene:767714 (1),  Ensembl(GRCz11):ENSDARG00000002710 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2078Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022357Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11342 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37569 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39385 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ncl N/A 1
    DISEASE ASSOCIATED WITH ncl HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ncl VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart looping (more)
    Cellular Component nucleolus (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript ncl-203 (1)    Ensembl 2671
    mRNA ncl-202 (1)    Ensembl 3219
    ncRNA ncl-003 (1)    Ensembl 710
    ncl-004 (1)    Ensembl 456
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ncl No data available
    MARKER RELATIONSHIPS
    ncl Contained in: [Fosmid] CH1073-141J18 (1), CH1073-352H10 (1)
    ncl Encodes: [EST] fa12d03
    [cDNA] MGC:152810 (1), MGC:194003 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001076652 (1) 2798 nt
    Genomic GenBank:CU469540 (1) 33245 nt
    Select Tool
    Polypeptide UniProtKB:B3DH54 (1) 708 aa
    Sequence Information (all 28)
    ORTHOLOGY for ncl ( Chr: 22 )
    CITATIONS (36)