ZFIN ID: ZDB-GENE-030131-6896
Gene Name: La ribonucleoprotein 7, transcriptional regulator
Gene Symbol: larp7    Nomenclature History

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Previous Names: fa10g04, wu:fa10g04, zgc:56476

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Involved in cardiac muscle tissue regeneration and regulation of cardiac muscle cell proliferation. Predicted to localize to nucleoplasm and ribonucleoprotein complex. Is expressed in blastoderm cell and brain. Orthologous to human LARP7 (La ribonucleoprotein 7, transcriptional regulator).
Genome Resources: Alliance (1),  Gene:334956 (1),  Ensembl(GRCz11):ENSDARG00000017315 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56476]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14775 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21105 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-larp7 N/A 2
    MO2-larp7 N/A 2
    MO3-larp7 N/A 1
    DISEASE ASSOCIATED WITH larp7 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Alazami syndrome 615071
    DISEASE ASSOCIATED WITH larp7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac muscle tissue regeneration (more)
    Cellular Component nucleus (more)
    Molecular Function 7SK snRNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM larp7 No data available
    MARKER RELATIONSHIPS
    larp7 Encodes: [EST] fa10g04
    [cDNA] MGC:56476 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199930 (1)
    Genomic GenBank:CABZ01043644 (1) 34881 nt
    Select Tool
    Polypeptide UniProtKB:E7F7F2 (1) 555 aa
    Sequence Information (all 17)
    ORTHOLOGY for larp7 ( Chr: 7 )
    CITATIONS (25)