ZFIN ID: ZDB-GENE-030131-681
Gene Name: myocardin related transcription factor Ab
Gene Symbol: mrtfab    Nomenclature History

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Previous Names: fb39e12, mkl1b, wu:fb39e12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and smooth muscle cell differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in megakaryocytic leukemia. Orthologous to human MRTFA (myocardin related transcription factor A).
Genome Resources: Alliance (1),  Gene:559638 (1),  Ensembl(GRCz11):ENSDARG00000076229 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38884 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44757 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mrtfab HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Immunodeficiency 66 618847
    DISEASE ASSOCIATED WITH mrtfab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription via serum response element binding (more)
    Cellular Component cytoplasm (more)
    Molecular Function actin binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mrtfab-201 (1)    Ensembl 730
    mrtfab-202 (1)    Ensembl 4810
    mrtfab-203 (1)    Ensembl 501
    mrtfab-204 (1)    Ensembl 873
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mrtfab No data available
    MARKER RELATIONSHIPS
    mrtfab Contained in: [BAC] CH73-136O9 (1), CH211-147H1 (1)
    mrtfab Encodes: [EST] fb39e12
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001201558 (1) 4538 nt
    Genomic GenBank:AL772266 (1) 179911 nt
    Select Tool
    Polypeptide UniProtKB:E7F9J6 (1) 1200 aa
    Sequence Information (all 26)
    ORTHOLOGY for mrtfab ( Chr: 12 )
    CITATIONS (15)