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Gene

cpt2

ID
ZDB-GENE-030131-6719
Name
carnitine palmitoyltransferase 2
Symbol
cpt2 Nomenclature History
Previous Names
  • wu:fa03e08
  • wu:fb54a02
  • zgc:101627
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in liver. Human ortholog(s) of this gene implicated in brain disease; lipid metabolism disorder; and muscular disease. Orthologous to human CPT2 (carnitine palmitoyltransferase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cpt2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
carnitine palmitoyltransferase II deficiency Alliance CPT II deficiency, infantile 600649
carnitine palmitoyltransferase II deficiency Alliance CPT II deficiency, lethal neonatal 608836
carnitine palmitoyltransferase II deficiency Alliance CPT II deficiency, myopathic, stress-induced 255110
{Encephalopathy, acute, infection-induced, 4, susceptibility to} 614212
Associated With cpt2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR039551 Choline/carnitine acyltransferase domain
Family IPR000542 Acyltransferase ChoActase/COT/CPT
Homologous_superfamily IPR042231 Choline/Carnitine o-acyltransferase, domain 2
Homologous_superfamily IPR042232 Choline/Carnitine o-acyltransferase, domain 1
Domain Details Per Protein
Protein Length Acyltransferase ChoActase/COT/CPT Choline/carnitine acyltransferase domain Choline/Carnitine o-acyltransferase, domain 1 Choline/Carnitine o-acyltransferase, domain 2
UniProtKB:B0S7W8 244
UniProtKB:B2GQ15 668
UniProtKB:A0A2R8Q0N5 669
UniProtKB:Q5U3U3 669
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations