Gene

vps41

ID
ZDB-GENE-030131-6671
Name
VPS41 subunit of HOPS complex
Symbol
vps41 Nomenclature History
Previous Names
  • fa01f11
  • si:ch211-146l10.2 (1)
  • wu:fa01f11 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity. Predicted to be involved in protein targeting to vacuole; regulation of SNARE complex assembly; and vacuole fusion, non-autophagic. Predicted to localize to HOPS complex and late endosome. Orthologous to human VPS41 (VPS41 subunit of HOPS complex).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Sanderson et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps41 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 29 Alliance Spinocerebellar ataxia, autosomal recessive 29 619389
Associated With vps41 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Family IPR016902 Vacuolar protein sorting-associated protein 41
Family IPR045111 Vacuolar protein sorting-associated protein Vps41/Vps8
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR000547 Clathrin, heavy chain/VPS, 7-fold repeat
Domain Details Per Protein
Protein Length Clathrin, heavy chain/VPS, 7-fold repeat Tetratricopeptide-like helical domain superfamily Vacuolar protein sorting-associated protein 41 Vacuolar protein sorting-associated protein Vps41/Vps8 WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily Zinc finger, RING-type
UniProtKB:E7F590 854
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations