Gene
vps41
- ID
- ZDB-GENE-030131-6671
- Name
- VPS41 subunit of HOPS complex
- Symbol
- vps41 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Predicted to be involved in protein targeting to vacuole; regulation of SNARE complex assembly; and vacuole fusion, non-autophagic. Predicted to localize to HOPS complex and late endosome. Orthologous to human VPS41 (VPS41 subunit of HOPS complex).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Sanderson et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive spinocerebellar ataxia 29 | Alliance | Spinocerebellar ataxia, autosomal recessive 29 | 619389 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001841 | Zinc finger, RING-type |
Family | IPR016902 | Vacuolar protein sorting-associated protein 41 |
Family | IPR045111 | Vacuolar protein sorting-associated protein Vps41/Vps8 |
Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
Repeat | IPR000547 | Clathrin, heavy chain/VPS, 7-fold repeat |
Domain Details Per Protein
Protein | Length | Clathrin, heavy chain/VPS, 7-fold repeat | Tetratricopeptide-like helical domain superfamily | Vacuolar protein sorting-associated protein 41 | Vacuolar protein sorting-associated protein Vps41/Vps8 | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | Zinc finger, RING-type |
---|---|---|---|---|---|---|---|---|
UniProtKB:E7F590
|
854 |
Interactions and Pathways
No data available
Plasmids
No data available