Gene

phb

ID
ZDB-GENE-030131-6577
Name
prohibitin
Symbol
phb Nomenclature History
Previous Names
  • fa18f07
  • fb09f05
  • sr:nyz128
  • wu:fa18f07 (1)
  • wu:fb09f05 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to localize to mitochondrial inner membrane. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; midbrain; and musculature system. Human ortholog(s) of this gene implicated in breast cancer and sporadic breast cancer. Orthologous to human PHB (prohibitin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With phb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
breast cancer Alliance {Breast cancer, susceptibility to} 114480
Associated With phb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001107 Band 7 domain
Family IPR000163 Prohibitin
Homologous_superfamily IPR036013 Band 7/SPFH domain superfamily
Domain Details Per Protein
Protein Length Band 7 domain Band 7/SPFH domain superfamily Prohibitin
UniProtKB:A0A8M2BB12 309
UniProtKB:Q7T1D8 271
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations