ZFIN ID: ZDB-GENE-030131-6559
Gene Name: ubiquitin protein ligase E3 component n-recognin 5
Gene Symbol: ubr5    Nomenclature History

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Previous Names: edd1 (1), wu:fa16c12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have several functions, including ubiquitin binding activity; ubiquitin-protein transferase activity; and zinc ion binding activity. Predicted to be involved in several processes, including negative regulation of histone H2A K63-linked ubiquitination; protein polyubiquitination; and regulation of double-strand break repair. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human UBR5 (ubiquitin protein ligase E3 component n-recognin 5).
Genome Resources: Alliance (1),  Gene:334627 (1),  Ensembl(GRCz11):ENSDARG00000018192 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ubr5 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ubr5 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to DNA damage stimulus (more)
Cellular Component nucleus (more)
Molecular Function RNA binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ubr5 No data available
MARKER RELATIONSHIPS
ubr5 Contained in: [BAC] CH211-135D14 (1)
ubr5 Encodes: [EST] fa16c12, IMAGE:6963255
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001164394 (1)
Genomic GenBank:CR293507 (1) 178271 nt
Select Tool
Polypeptide UniProtKB:F1Q8J2 (1) 2795 aa
Sequence Information (all 29)
ORTHOLOGY for ubr5 ( Chr: 16 )
CITATIONS (25)