Gene

ubr5

ID
ZDB-GENE-030131-6559
Name
ubiquitin protein ligase E3 component n-recognin 5
Symbol
ubr5 Nomenclature History
Previous Names
  • edd1 (1)
  • wu:fa16c12
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have several functions, including ubiquitin binding activity; ubiquitin-protein transferase activity; and zinc ion binding activity. Predicted to be involved in several processes, including negative regulation of histone H2A K63-linked ubiquitination; protein polyubiquitination; and regulation of double-strand break repair. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human UBR5 (ubiquitin protein ligase E3 component n-recognin 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ubr5 Human Ortholog
No data available
Associated With ubr5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000569 HECT domain
Domain IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein
Domain IPR003126 Zinc finger, UBR-type
Domain IPR024725 E3 ubiquitin ligase EDD, ubiquitin-associated domain
Homologous_superfamily IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Homologous_superfamily IPR035983 HECT, E3 ligase catalytic domain
Homologous_superfamily IPR036053 PABC (PABP) domain
Domain Details Per Protein
Protein Length E3 ubiquitin ligase EDD, ubiquitin-associated domain HECT domain HECT, E3 ligase catalytic domain PABC (PABP) domain Polyadenylate-binding protein/Hyperplastic disc protein Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Zinc finger, UBR-type
UniProtKB:Q08C54 530
UniProtKB:F1Q8J2 2795
UniProtKB:Q642I4 1790
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations