ZFIN ID: ZDB-GENE-030131-6529
Gene Name: protein phosphatase 1, catalytic subunit, beta isoform, like
Gene Symbol: ppp1cbl    Nomenclature History

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Previous Names: PPP1CBb (1), ppp1cbb (1), wu:fa14b10, zgc:64169

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits protein heterodimerization activity. Involved in convergent extension involved in axis elongation. Predicted to localize to cytoplasm and nucleus. Orthologous to human PPP1CB (protein phosphatase 1 catalytic subunit beta).
Genome Resources: Alliance (1),  Gene:334597 (1),  Ensembl(GRCz11):ENSDARG00000102012 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7142005]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-ppp1cbl N/A 1
DISEASE ASSOCIATED WITH ppp1cbl HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Noonan syndrome-like disorder with loose anagen hair 2 Alliance Noonan syndrome-like disorder with loose anagen hair 2 617506
DISEASE ASSOCIATED WITH ppp1cbl VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process convergent extension involved in axis elongation (more)
Cellular Component cytoplasm (more)
Molecular Function protein heterodimerization activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
ncRNA ppp1cbl-001 (1) 688
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ppp1cbl No data available
MARKER RELATIONSHIPS
ppp1cbl Encodes: [EST] fa14b10, IMAGE:7142005 (1)
[cDNA] MGC:64169 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_199916 (1) 1271 nt
Genomic GenBank:CABZ01081392 (1) 5509 nt
Polypeptide UniProtKB:Q7T313 (1) 281 aa
Sequence Information (all 13)
ORTHOLOGY for ppp1cbl ( Chr: 7 )
CITATIONS (20)