Gene

prkcda

ID
ZDB-GENE-030131-6503
Name
protein kinase C, delta a
Symbol
prkcda Nomenclature History
Previous Names
  • prkcd
  • fb09d10
  • fv43b11
  • wu:fb09d10
  • wu:fv43b11
  • zgc:56558
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Localizes to immunological synapse. Is expressed in blood; myotome; nervous system; otic vesicle; and somite. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3; fatty liver disease; and hypertension. Orthologous to human PRKCD (protein kinase C delta).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkcda Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autoimmune lymphoproliferative syndrome type 3 Alliance Autoimmune lymphoproliferative syndrome, type III 615559
Associated With prkcda Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR017892 Protein kinase, C-terminal
Domain IPR020454 Diacylglycerol/phorbol-ester binding
Domain IPR034667 Novel protein kinase C delta, catalytic domain
Family IPR014376 Protein kinase C, delta/epsilon/eta/theta types
Family IPR027436 Protein kinase C, delta
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C2 domain superfamily Diacylglycerol/phorbol-ester binding Novel protein kinase C delta, catalytic domain Protein kinase, ATP binding site Protein kinase C, delta Protein kinase C, delta/epsilon/eta/theta types Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q7ZUC5 684
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations