ZFIN ID: ZDB-GENE-030131-6497
Gene Name: mitogen-activated protein kinase kinase kinase kinase 5
Gene Symbol: map4k5    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fl74c10, wu:fl74c10, zgc:55719 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have MAP kinase kinase kinase kinase activity. Predicted to be involved in activation of protein kinase activity; signal transduction by protein phosphorylation; and stress-activated protein kinase signaling cascade. Predicted to localize to the cytoplasm. Orthologous to human MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5).
Genome Resources: Alliance (1),  Gene:334565 (1),  Ensembl(GRCz11):ENSDARG00000039125 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55719]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31950 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35558 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH map4k5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH map4k5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Binding_site IPR017441 Protein kinase, ATP binding site
    Domain IPR000719 Protein kinase domain
    Domain IPR001180 Citron homology (CNH) domain
    Family IPR021160 Mitogen-activated protein (MAP) kinase kinase kinase kinase
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA map4k5-201 (1)    Ensembl 3735
    map4k5-202 (1)    Ensembl 745
    ncRNA map4k5-003 (1) 485
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM map4k5 No data available
    MARKER RELATIONSHIPS
    map4k5 Contained in: [BAC] CH211-282C13 (1), DKEY-69E12 (1) (order this)
    map4k5 Encodes: [EST] fl74c10
    [cDNA] MGC:55719 (1), MGC:55985 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199913 (1) 3755 nt
    Genomic GenBank:BX936452 (1) 136110 nt
    Select Tool
    Polypeptide UniProtKB:B8A6G9 (1) 878 aa
    Sequence Information (all 34)
    ORTHOLOGY for map4k5 ( Chr: 13 )
    CITATIONS (27)