ZFIN ID: ZDB-GENE-030131-6435
Gene Name: RIC8 guanine nucleotide exchange factor B
Gene Symbol: ric8b    Nomenclature History

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Previous Names: fj97c10, synbl, synembryn like, wu:fj97c10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have G-protein alpha-subunit binding activity; GTPase activator activity; and guanyl-nucleotide exchange factor activity. Involved in pigment cell development. Predicted to localize to cytoplasm and plasma membrane. Orthologous to human RIC8B (RIC8 guanine nucleotide exchange factor B).
Genome Resources: Alliance (1),  Gene:334503 (1),  Ensembl(GRCz11):ENSDARG00000005972 (1)
GENE EXPRESSION
All Expression Data: Fig. 6 from Nagayoshi et al., 2008
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2039aTg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1716 Point Mutation Unknown Premature Stop ENU
    sa13369 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17855 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36602 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36603 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ric8b N/A 1
    DISEASE ASSOCIATED WITH ric8b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ric8b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process pigment cell development (more)
    Cellular Component cytoplasm (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ric8b-201 (1)    Ensembl 1840
    ncRNA ric8b-002 (1)    Ensembl 414
    ric8b-003 (1)    Ensembl 732
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ric8b No data available
    MARKER RELATIONSHIPS
    ric8b Contained in: [BAC] DKEY-103I16 (1) (order this), DKEY-227K11 (1) (order this)
    ric8b Encodes: [EST] fj97c10
    [cDNA] MGC:136358 (1), MGC:162835 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001005293 (1) 1801 nt
    Genomic GenBank:BX465207 (1) 265632 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q1JQ20 (1) 536 aa
    Sequence Information (all 27)
    ORTHOLOGY for ric8b ( Chr: 18 )
    CITATIONS (29)