Gene
hnrnpub
- ID
- ZDB-GENE-030131-6422
- Name
- heterogeneous nuclear ribonucleoprotein Ub
- Symbol
- hnrnpub Nomenclature History
- Previous Names
-
- hnrnpu
- hnrpu (1)
- wu:fa66f11
- wu:fc18b08
- wu:fi89c08
- zgc:111835
- zgc:136480
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have several functions, including basal RNA polymerase II transcription machinery binding activity; nucleic acid binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in RNA localization to chromatin; regulation of nucleobase-containing compound metabolic process; and regulation of organelle organization. Predicted to colocalize with RNA polymerase II transcription regulator complex. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 54. Orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U).
- Genome Resources
- Note
- None
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 54 | Alliance | Developmental and epileptic encephalopathy 54 | 617391 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003034 | SAP domain |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR035778 | Heterogeneous nuclear ribonucleoprotein U, SPRY domain |
| Family | IPR026745 | Heterogeneous nuclear ribonucleoprotein U |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036361 | SAP domain superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Heterogeneous nuclear ribonucleoprotein U | Heterogeneous nuclear ribonucleoprotein U, SPRY domain | P-loop containing nucleoside triphosphate hydrolase | SAP domain | SAP domain superfamily | SPRY domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5RHQ7
|
796 | |||||||||
|
UniProtKB:Q1ECZ7
|
795 | |||||||||
|
UniProtKB:Q6PYX3
|
652 | |||||||||
|
UniProtKB:Q498X5
|
788 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
hnrnpub-202
(1)
|
4350 nt | |
| ncRNA |
hnrnpub-002
(1)
|
406 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl