ZFIN ID: ZDB-GENE-030131-6414
Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Gene Symbol: abcb5    Nomenclature History

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Previous Names: abcb1a (1), im:7158730, MDR1 (1), wu:fc18f02, wu:fi81f06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have ATPase-coupled transmembrane transporter activity. Involved in detoxification of mercury ion. Predicted to localize to integral component of membrane. Is expressed in EVL; epidermis; liver; periderm; and pharyngeal arch. Orthologous to human ABCB5 (ATP binding cassette subfamily B member 5).
Genome Resources: Alliance (1),  Gene:798527 (1),  Ensembl(GRCz11):ENSDARG00000021787 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 4 publications
Directly Submitted Expression Data: 7 figures (13 images) from Thisse et al., 2004 [IMAGE:7158730]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2844 Point Mutation Unknown Splice Site ENU
sa8683 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42702 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-abcb5 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abcb5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH abcb5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process detoxification of mercury ion (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abcb5-201 (1)    Ensembl 5011
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcb5 No data available
    MARKER RELATIONSHIPS
    abcb5 Contained in: [BAC] CH73-226D12 (1), CH211-180P9 (1)
    abcb5 Encodes: [EST] fc18f02, fi81f06, IMAGE:7158730 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001922682 (1) 5334 nt
    Genomic GenBank:BX005032 (1) 155001 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QDG3 (1) 1350 aa
    Sequence Information (all 36)
    ORTHOLOGY for abcb5 ( Chr: 16 )
    CITATIONS (41)