ZFIN ID: ZDB-GENE-030131-6403
Gene Name: La ribonucleoprotein 6, translational regulator a
Gene Symbol: larp6a    Nomenclature History

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Previous Names: achn (1), larp6 (1), acheron (1), fi75f12, wu:fi75f12, zgc:66107

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Exhibits RNA binding activity. Involved in somitogenesis. Predicted to localize to the nucleus and ribonucleoprotein complex. Is expressed in central nervous system; mesenchymal cell; segmental plate; and somite. Orthologous to human LARP6 (La ribonucleoprotein 6, translational regulator).
Genome Resources: Alliance (1),  Gene:334471 (1),  Ensembl(GRCz11):ENSDARG00000005355 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (5 images) from Thisse et al., 2005 [eu362]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-larp6a N/A 1
MO2-larp6a N/A 1
MO3-larp6a N/A 1
DISEASE ASSOCIATED WITH larp6a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH larp6a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process somitogenesis (more)
Cellular Component nucleus (more)
Molecular Function RNA binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR002344 Lupus La protein
Domain IPR006630 La-type HTH domain
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Domain IPR024642 SUZ-C domain
Domain IPR034880 La-related protein 6, RNA recognition motif
Family IPR034886 La-related protein 6
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA larp6a-201 (1)    Ensembl 1877
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM larp6a No data available
MARKER RELATIONSHIPS
larp6a Contained in: [Fosmid] ZFOS-508H5 (1)
larp6a Encodes: [EST] eu362 (1), fi75f12
[cDNA] MGC:66107 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_199903 (1) 2259 bp
Genomic GenBank:CU651575 (1) 36934 bp
Select Tool
Polypeptide UniProtKB:Q6PHD4 (1) 485 aa
Sequence Information (all 13)
ORTHOLOGY for larp6a ( Chr: 18 )
CITATIONS (23)