ZFIN is now using GRCz12tu for Genomic Data
Gene
cdk5rap2
- ID
- ZDB-GENE-030131-6392
- Name
- CDK5 regulatory subunit associated protein 2
- Symbol
- cdk5rap2 Nomenclature History
- Previous Names
-
- cep215 (1)
- fi74c05
- wu:fi74c05
- zgc:55582
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable molecular adaptor activity. Predicted to be involved in centrosome cycle and regulation of Golgi organization. Predicted to be located in cytoplasm and microtubule organizing center. Predicted to be active in Golgi apparatus and centrosome. Human ortholog(s) of this gene implicated in Seckel syndrome; microcephaly; and primary autosomal recessive microcephaly 3. Orthologous to human CDK5RAP2 (CDK5 regulatory subunit associated protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55582 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 3 | Alliance | Microcephaly 3, primary, autosomal recessive | 604804 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CDK5 regulatory subunit-associated protein 2/Myomegalin, coiled coil | Centrosomin, N-terminal motif 1 | Microtubule-associated AKAP9-binding protein |
|---|---|---|---|---|---|
| UniProtKB:A0A8M3ALW0 | InterPro | 2873 | |||
| UniProtKB:A0A8M3AWK4 | InterPro | 2871 | |||
| UniProtKB:A0A8M3AL71 | InterPro | 2912 | |||
| UniProtKB:A0A8M3ATJ9 | InterPro | 2913 | |||
| UniProtKB:Q802Z7 | InterPro | 1208 | |||
| UniProtKB:A0A8M3ATK8 | InterPro | 2866 | |||
| UniProtKB:A0A8M3AL75 | InterPro | 2841 | |||
| UniProtKB:A0A8M3B4F9 | InterPro | 2878 | |||
| UniProtKB:A0AB13A9N4 | InterPro | 2749 | |||
| UniProtKB:A0AB32T7M1 | InterPro | 2870 | |||
| UniProtKB:A0AB32T7M2 | InterPro | 2865 | |||
| UniProtKB:A0AB32T8Y6 | InterPro | 2824 | |||
| UniProtKB:A0AB32T9E0 | InterPro | 2823 | |||
| UniProtKB:A0AB32TA56 | InterPro | 2789 | |||
| UniProtKB:A0AB32TD62 | InterPro | 2830 | |||
| UniProtKB:A0AB32TF15 | InterPro | 2288 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:55582-201
(1)
|
Ensembl | 3,835 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers