ZFIN ID: ZDB-GENE-030131-6367
Gene Name: phospholipase C, eta 2a
Gene Symbol: plch2a    Nomenclature History

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Previous Names: fi61g08, si:ch211-251b21.2 (1), wu:fi61g08 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol phospholipase C activity. Predicted to be involved in inositol trisphosphate biosynthetic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Orthologous to human PLCH2 (phospholipase C eta 2).
Genome Resources: Alliance (1),  Gene:100334231 (1),  Ensembl(GRCz11):ENSDARG00000059960 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a314 Complex Unknown Unknown CRISPR
sa25407 Point Mutation Unknown Premature Stop ENU
sa34490 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-plch2a 1
    CRISPR2-plch2a 1
    CRISPR3-plch2a 1
    CRISPR4-plch2a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH plch2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH plch2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA plch2a-202 (1)    Ensembl 4166
    ncRNA plch2a-002 (1) 942
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM plch2a No data available
    MARKER RELATIONSHIPS
    plch2a Contained in: [BAC] CH211-251B21 (1)
    plch2a Encodes: [EST] fi61g08
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001347692 (1)
    Genomic GenBank:CU499311 (1) 142016 nt
    Select Tool
    Polypeptide UniProtKB:F1QAP6 (1) 1534 aa
    Sequence Information (all 27)
    ORTHOLOGY for plch2a ( Chr: 8 )
    CITATIONS (20)