ZFIN ID: ZDB-GENE-030131-6305
Gene Name: F-box and WD repeat domain containing 11a
Gene Symbol: fbxw11a    Nomenclature History

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Previous Names: btrc2, fbxw11, wu:fd14d12 (1), wu:fi43f07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have snoRNA binding activity. Involved in sprouting angiogenesis. Predicted to localize to small-subunit processome. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11).
Genome Resources: Alliance (1),  Gene:334373 (1),  Ensembl(GRCz11):ENSDARG00000104806 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55481]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:6912104]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7147071]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018852Tg Transgenic Insertion Unknown Unknown DNA
sa12221 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31968 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42328 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-fbxw11a N/A 1
    MO2-fbxw11a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fbxw11a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Neurodevelopmental, jaw, eye, and digital syndrome 618914
    DISEASE ASSOCIATED WITH fbxw11a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sprouting angiogenesis (more)
    Cellular Component small-subunit processome (more)
    Molecular Function protein dimerization activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fbxw11a No data available
    MARKER RELATIONSHIPS
    fbxw11a Contains: [SNP] rs3728615 (1), rs3728616 (1), rs3728617 (1)
    fbxw11a Encodes: [EST] fd14d12, fi43f07, IMAGE:6912104 (1), IMAGE:7147071 (1)
    [cDNA] MGC:55481 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201310 (1) 2530 nt
    Genomic GenBank:CABZ01001946 (1) 23002 nt
    Polypeptide UniProtKB:A0A2R8QFQ6 (1) 562 aa
    Sequence Information (all 20)
    ORTHOLOGY for fbxw11a ( Chr: 14 )
    CITATIONS (29)