Gene
arhgef10
- ID
- ZDB-GENE-030131-6210
- Name
- Rho guanine nucleotide exchange factor (GEF) 10
- Symbol
- arhgef10 Nomenclature History
- Previous Names
-
- wu:fi38h08
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in actin cytoskeleton organization; mitotic spindle assembly; and positive regulation of stress fiber assembly. Predicted to localize to centrosome. Orthologous to human ARHGEF10 (Rho guanine nucleotide exchange factor 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
?Slowed nerve conduction velocity, AD | 608236 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000219 | Dbl homology (DH) domain |
Family | IPR030632 | Rho guanine nucleotide exchange factor 10 |
Family | IPR039919 | Rho guanine nucleotide exchange factor 10/17 |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
Domain Details Per Protein
Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Rho guanine nucleotide exchange factor 10 | Rho guanine nucleotide exchange factor 10/17 | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:E7F3Z6
|
1239 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
arhgef10-202
(1)
|
4004 nt | |
ncRNA |
arhgef10-002
(1)
|
780 nt | |
ncRNA |
arhgef10-003
(1)
|
296 nt |
Interactions and Pathways
No data available
Plasmids
No data available