ZFIN ID: ZDB-GENE-030131-616
Gene Name: guanine nucleotide binding protein-like 3 (nucleolar)
Gene Symbol: gnl3    Nomenclature History

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Previous Names: id:ibd2914, nstm (1), nucleostemin, wu:fb38a04, wu:fc55d07, zgc:123093

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have GTP binding activity. Involved in several processes, including exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neural retina development; and regulation of exit from mitosis. Predicted to localize to nucleolus. Is expressed in head; immature eye; midbrain; and somite. Orthologous to human GNL3 (G protein nucleolar 3).
Genome Resources: Alliance (1),  Gene:321897 (1),  Ensembl(GRCz11):ENSDARG00000006219 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 3 figures (5 images) from Kudoh et al., 2001 [ibd2914]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-15 (30.0h-36.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi299Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hu3259 Point Mutation Exon 5 Premature Stop
    sa41766 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • DISEASE ASSOCIATED WITH gnl3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gnl3 VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gnl3-202 (1)    Ensembl 2090
    ncRNA gnl3-002 (1)    Ensembl 773
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gnl3 No data available
    MARKER RELATIONSHIPS
    gnl3 Contained in: [BAC] CH211-80B12 (1)
    gnl3 Encodes: [EST] fb38a04, fc55d07, ibd2914
    [cDNA] MGC:123093 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002297 (1) 2074 nt
    Genomic GenBank:CR450797 (1) 101488 nt
    Select Tool
    Polypeptide UniProtKB:F1QGN5 (1) 561 aa
    Sequence Information (all 23)
    ORTHOLOGY for gnl3 ( Chr: 11 )
    CITATIONS (35)