Gene

gnl3

ID
ZDB-GENE-030131-616
Name
guanine nucleotide binding protein-like 3 (nucleolar)
Symbol
gnl3 Nomenclature History
Previous Names
  • id:ibd2914
  • nstm (1)
  • nucleostemin
  • wu:fb38a04
  • wu:fc55d07
  • zgc:123093
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have GTP binding activity. Involved in several processes, including exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neural retina development; and regulation of exit from mitosis. Predicted to localize to nucleolus. Is expressed in head; immature eye; midbrain; and somite. Orthologous to human GNL3 (G protein nucleolar 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnl3 Human Ortholog
No data available
Associated With gnl3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006073 GTP binding domain
Domain IPR014813 Guanine nucleotide-binding protein-like 3, N-terminal domain
Domain IPR030378 Circularly permuted (CP)-type guanine nucleotide-binding (G) domain
Homologous_superfamily IPR023179 GTP-binding protein, orthogonal bundle domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Circularly permuted (CP)-type guanine nucleotide-binding (G) domain GTP binding domain GTP-binding protein, orthogonal bundle domain superfamily Guanine nucleotide-binding protein-like 3, N-terminal domain P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q32PN9 561
UniProtKB:Q6DRP2 561
UniProtKB:Q567V7 499
UniProtKB:F1QGN5 561
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations