ZFIN ID: ZDB-GENE-030131-6134
Gene Name: polo-like kinase 3 (Drosophila)
Gene Symbol: plk3    Nomenclature History

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Previous Names: cnk (1), wu:fi35f10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in Golgi disassembly; cellular response to DNA damage stimulus; and regulation of cell cycle process. Predicted to localize to cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in liver; spinal cord; and spleen. Orthologous to human PLK3 (polo like kinase 3).
Genome Resources: Alliance (1),  Gene:334202 (1),  Ensembl(GRCz11):ENSDARG00000038754 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7144737]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023631Tg Transgenic Insertion Unknown Unknown DNA
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-plk3 N/A 1
MO2-plk3 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH plk3 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH plk3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component centrosome (more)
Molecular Function ATP binding (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA plk3-202 (1)    Ensembl 3306
ncRNA plk3-002 (1)    Ensembl 915
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM plk3 No data available
MARKER RELATIONSHIPS
plk3 Contained in: [BAC] DKEY-4I23 (1) (order this)
[Fosmid] CH1073-225K6 (1)
plk3 Contains: [SNP] rs3727637 (1), rs3727638 (1), rs3727639 (1)
plk3 Encodes: [EST] fi35f10, IMAGE:7144737 (1)
[cDNA] MGC:55899 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_201308 (1) 3301 nt
Genomic GenBank:BX537326 237869 nt Blast at MegaBLAST
Polypeptide UniProtKB:B0S6K2 (1) 660 aa
Sequence Information (all 17)
ORTHOLOGY for plk3 ( Chr: 2 )
CITATIONS (32)