Gene

plk3

ID
ZDB-GENE-030131-6134
Name
polo-like kinase 3 (Drosophila)
Symbol
plk3 Nomenclature History
Previous Names
  • cnk (1)
  • wu:fi35f10
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in Golgi disassembly; cellular response to DNA damage stimulus; and regulation of cell cycle process. Predicted to localize to cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in liver; spinal cord; and spleen. Orthologous to human PLK3 (polo like kinase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plk3 Human Ortholog
No data available
Associated With plk3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000959 POLO box domain
Domain IPR033695 Second polo-box domain
Domain IPR033701 First polo-box domain
Domain IPR042703 Serine/threonine-protein kinase PLK3, catalytic domain
Family IPR020658 Serine/threonine-protein kinase Plk3
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036947 POLO box domain superfamily
Domain Details Per Protein
Protein Length First polo-box domain POLO box domain POLO box domain superfamily Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Second polo-box domain Serine/threonine-protein kinase, active site Serine/threonine-protein kinase Plk3 Serine/threonine-protein kinase PLK3, catalytic domain
UniProtKB:B0S6K2 660
UniProtKB:D9IWE5 644
UniProtKB:Q7ZVM4 644
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations