Gene

aldh7a1

ID
ZDB-GENE-030131-6129
Name
aldehyde dehydrogenase 7 family, member A1
Symbol
aldh7a1 Nomenclature History
Previous Names
  • ATQ (1)
  • wu:fi34d12
  • wu:fi35e06
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Enables alpha-aminoadipate acetyltransferase activity. Acts upstream of or within camera-type eye development; cartilage development; and pectoral fin development. Is expressed in several structures, including alar plate midbrain region; fin bud; musculature system; nervous system; and pharyngeal arch. Used to study epilepsy and pyridoxine-dependent epilepsy. Human ortholog(s) of this gene implicated in pyridoxine-dependent epilepsy. Orthologous to human ALDH7A1 (aldehyde dehydrogenase 7 family member A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
16 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldh7a1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pyridoxine-dependent epilepsy Alliance Epilepsy, pyridoxine-dependent 266100
Associated With aldh7a1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR029510 Aldehyde dehydrogenase, glutamic acid active site
Domain IPR015590 Aldehyde dehydrogenase domain
Homologous_superfamily IPR016161 Aldehyde/histidinol dehydrogenase
Homologous_superfamily IPR016162 Aldehyde dehydrogenase, N-terminal
Homologous_superfamily IPR016163 Aldehyde dehydrogenase, C-terminal
Domain Details Per Protein
Protein Length Aldehyde dehydrogenase, C-terminal Aldehyde dehydrogenase domain Aldehyde dehydrogenase, glutamic acid active site Aldehyde dehydrogenase, N-terminal Aldehyde/histidinol dehydrogenase
UniProtKB:Q803R9 511
UniProtKB:F1QR17 541
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations