Gene

hgs

ID
ZDB-GENE-030131-6107
Name
hepatocyte growth factor-regulated tyrosine kinase substrate
Symbol
hgs Nomenclature History
Previous Names
  • fi34f05
  • wu:fi34f05
  • zgc:63492 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable kinase activity and metal ion binding activity. Predicted to act upstream of or within intracellular protein transport and phosphorylation. Predicted to be located in early endosome membrane. Orthologous to human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hgs Human Ortholog
No data available
Associated With hgs Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003903 Ubiquitin interacting motif
Domain IPR000306 FYVE zinc finger
Domain IPR002014 VHS domain
Domain IPR017455 Zinc finger, FYVE-related
Domain IPR024641 Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain
Family IPR017073 Ubiquitin binding protein, Hrs/VPS27
Homologous_superfamily IPR008942 ENTH/VHS
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length ENTH/VHS FYVE zinc finger Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain Ubiquitin binding protein, Hrs/VPS27 Ubiquitin interacting motif VHS domain Zinc finger, FYVE/PHD-type Zinc finger, FYVE-related Zinc finger, RING/FYVE/PHD-type
UniProtKB:E9QCS7 757
UniProtKB:Q6PH00 447
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations