ZFIN ID: ZDB-GENE-030131-6053
Gene Name: 3-hydroxyacyl-CoA dehydratase 2
Gene Symbol: hacd2    Nomenclature History

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Previous Names: ptplb, wu:fi32c08, zgc:55421

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have 3-hydroxyacyl-CoA dehydratase activity. Predicted to be involved in fatty acid elongation; sphingolipid biosynthetic process; and very long-chain fatty acid biosynthetic process. Predicted to localize to integral component of endoplasmic reticulum membrane. Orthologous to human HACD2 (3-hydroxyacyl-CoA dehydratase 2).
Genome Resources: Alliance (1),  Gene:334121 (1),  Ensembl(GRCz11):ENSDARG00000014806 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55421]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029601Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13302 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41481 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hacd2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hacd2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hacd2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fatty acid biosynthetic process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function 3-hydroxy-arachidoyl-CoA dehydratase activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hacd2-201 (1)    Ensembl 2129
    hacd2-202 (1)    Ensembl 725
    hacd2-203 (1)    Ensembl 961
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hacd2 No data available
    MARKER RELATIONSHIPS
    hacd2 Contained in: [BAC] DKEYP-60A7 (1)
    hacd2 Encodes: [EST] fi32c08
    [cDNA] MGC:55421 (1), MGC:192259 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199861 (1) 2107 nt
    Genomic GenBank:CR847515 (1) 153947 nt
    Select Tool
    Polypeptide UniProtKB:B0V199 (1) 244 aa
    Sequence Information (all 17)
    ORTHOLOGY for hacd2 ( Chr: 9 )
    CITATIONS (29)