Gene

ldb3b

ID
ZDB-GENE-030131-6032
Name
LIM domain binding 3b
Symbol
ldb3b Nomenclature History
Previous Names
  • ldb3l
  • wu:fi31d08
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have actin binding activity and muscle alpha-actinin binding activity. Predicted to be involved in actin cytoskeleton organization; heart development; and muscle structure development. Predicted to localize to Z disc; actin cytoskeleton; and adherens junction. Is expressed in cardiovascular system; musculature system; and somite. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1C; distal myopathy; and myofibrillar myopathy 4. Orthologous to human LDB3 (LIM domain binding 3).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ldb3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dilated cardiomyopathy 1C Alliance Cardiomyopathy, dilated, 1C, with or without LVNC 601493
dilated cardiomyopathy 1C Alliance Cardiomyopathy, hypertrophic, 24 601493
dilated cardiomyopathy 1C Alliance Left ventricular noncompaction 3 601493
myofibrillar myopathy 4 Alliance Myopathy, myofibrillar, 4 609452
Associated With ldb3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR006643 Zasp-like motif
Domain IPR031847 Domain of unknown function DUF4749
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF4749 PDZ domain PDZ superfamily Zasp-like motif
UniProtKB:A0A0J9YJJ2 174
UniProtKB:Q802V0 292
UniProtKB:A0A0R4IWD0 242
UniProtKB:A0A0R4IT29 214
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations