ZFIN ID: ZDB-GENE-030131-5990
Gene Name: WT1 associated protein
Gene Symbol: wtap    Nomenclature History

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Previous Name: wu:fi29a09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Involved in regulation of apoptotic process. Predicted to localize to the RNA N6-methyladenosine methyltransferase complex; cytoplasm; and nuclear speck. Is expressed in head. Orthologous to human WTAP (WT1 associated protein).
Genome Resources: Alliance (1),  Gene:334058 (1),  Ensembl(GRCz11):ENSDARG00000042642 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66202]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013854Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la021542Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32300 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wtap N/A 1
    DISEASE ASSOCIATED WITH wtap HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH wtap VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of apoptotic process (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR029732 WTAP/Mum2 family
    Family IPR033757 Pre-mRNA-splicing regulator WTAP
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wtap-201 (1)    Ensembl 2035
    wtap-202 (1)    Ensembl 1157
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wtap No data available
    MARKER RELATIONSHIPS
    wtap Contained in: [BAC] CH211-195E3 (1)
    wtap Encodes: [EST] fi29a09
    [cDNA] MGC:66202 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199853 (1) 1996 nt
    Genomic GenBank:AL929182 (1) 225515 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q7SXL7 (1) 423 aa
    Sequence Information (all 17)
    ORTHOLOGY for wtap ( Chr: 20 )
    CITATIONS (31)