ZFIN ID: ZDB-GENE-030131-5978
Gene Name: tRNA methyltransferase 5
Gene Symbol: trmt5    Nomenclature History

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Previous Name: wu:fi28b08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have tRNA (guanine-N1-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to localize to mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 26. Orthologous to human TRMT5 (tRNA methyltransferase 5).
Genome Resources: Alliance (1),  Gene:564078 (1),  Ensembl(GRCz11):ENSDARG00000069278 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2689 Point Mutation Unknown Premature Stop ENU
sa42236 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH trmt5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    combined oxidative phosphorylation deficiency 26 Alliance Combined oxidative phosphorylation deficiency 26 616539
    DISEASE ASSOCIATED WITH trmt5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process methylation (more)
    Cellular Component mitochondrial matrix (more)
    Molecular Function methyltransferase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA trmt5-201 (1)    Ensembl 1586
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM trmt5 No data available
    MARKER RELATIONSHIPS
    trmt5 Contained in: [BAC] CH211-202M24 (1)
    trmt5 Contains: [SNP] rs3728557 (1), rs3728558 (1), rs3728559 (1), rs3728560 (1), rs3728561 (1), rs3728562 (1)
    trmt5 Encodes: [EST] fi28b08
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001145583 (1)
    Genomic GenBank:BX537123 (1) 202967 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A7E2G9 (1) 481 aa
    Sequence Information (all 22)
    ORTHOLOGY for trmt5 ( Chr: 13 )
    CITATIONS (23)