ZFIN ID: ZDB-GENE-030131-5954
Gene Name: makorin, ring finger protein, 4
Gene Symbol: mkrn4    Nomenclature History

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Previous Names: fi27c05, si:ch73-237c6.4, wu:fi27c05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Is expressed in several structures, including eye; gill; gonad; integument; and liver. Orthologous to human MKRN6P (makorin ring finger protein 6, pseudogene).
Genome Resources: Alliance (1),  Gene:559882 (1),  Ensembl(GRCz11):ENSDARG00000028295 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Bohne et al., 2010
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16544 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27197 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mkrn4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mkrn4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Molecular Function metal ion binding (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR017907 Zinc finger, RING-type, conserved site
    Domain IPR000571 Zinc finger, CCCH-type
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR018957 Zinc finger, C3HC4 RING-type
    Domain IPR041367 E3 ligase, CCCH-type zinc finger
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Homologous_superfamily IPR036855 Zinc finger, CCCH-type superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mkrn4-201 (1)    Ensembl 1845
    mkrn4-202 (1)    Ensembl 575
    mkrn4-203 (1)    Ensembl 536
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mkrn4 No data available
    MARKER RELATIONSHIPS
    mkrn4 Contained in: [BAC] CH73-237C6 (1)
    mkrn4 Encodes: [EST] fi27c05
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001128336 (1) 1845 nt
    Genomic GenBank:CU302443 (1) 43687 nt
    Select Tool
    Polypeptide UniProtKB:A9C4A6 (1) 397 aa
    Sequence Information (all 13)
    ORTHOLOGY for mkrn4 ( Chr: 8 )
    CITATIONS (16)