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Gene

brdt

ID
ZDB-GENE-030131-5928
Name
bromodomain, testis-specific
Symbol
brdt Nomenclature History
Previous Names
  • fi25h02
  • si:dkeyp-85h7.3
  • wu:fi25h02 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in histone displacement; male gamete generation; and regulation of RNA metabolic process. Predicted to act upstream of or within cell differentiation; chromatin organization; and meiotic cell cycle. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in azoospermia; oligospermia; and spermatogenic failure 21. Orthologous to human BRDT (bromodomain testis associated).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With brdt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spermatogenic failure 21 Alliance ?Spermatogenic failure 21 617644
Associated With brdt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018359 Bromodomain, conserved site
Domain IPR001487 Bromodomain
Domain IPR027353 NET domain
Domain IPR031354 Bromodomain protein 4, C-terminal
Domain IPR043508 Brdt, bromodomain, repeat I
Domain IPR043509 Brdt, bromodomain, repeat II
Homologous_superfamily IPR036427 Bromodomain-like superfamily
Homologous_superfamily IPR038336 NET domain superfamily
Domain Details Per Protein
Protein Length Brdt, bromodomain, repeat I Brdt, bromodomain, repeat II Bromodomain Bromodomain, conserved site Bromodomain-like superfamily Bromodomain protein 4, C-terminal NET domain NET domain superfamily
UniProtKB:A0A0R4IJ54 979
UniProtKB:I3IS77 1093
UniProtKB:Q504G9 600
UniProtKB:A0A0R4IZU8 350
UniProtKB:F1QW93 918
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations