ZFIN ID: ZDB-GENE-030131-591
Gene Name: serine and arginine rich splicing factor 4
Gene Symbol: srsf4    Nomenclature History

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Previous Names: sfrs4, wu:fb37e02, wu:fj35e06, zgc:152957, zgc:55809 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to the nuclear speck. Orthologous to human SRSF4 (serine and arginine rich splicing factor 4).
Genome Resources: Alliance (1),  Gene:321872 (1),  Ensembl(GRCz11):ENSDARG00000105293 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55809]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013384Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH srsf4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH srsf4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mRNA cis splicing, via spliceosome (more)
    Cellular Component integral component of membrane (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000504 RNA recognition motif domain
    Domain IPR035585 Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1
    Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    Homologous_superfamily IPR035979 RNA-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA srsf4-202 (1)    Ensembl 1853
    srsf4-203 (1)    Ensembl 1124
    ncRNA srsf4-003 (1)    Ensembl 1953
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM srsf4 No data available
    MARKER RELATIONSHIPS
    srsf4 Contained in: [BAC] CH211-204A13 (1)
    srsf4 Encodes: [EST] fb37e02, fj35e06 (1)
    [STS] fi41a02 (1)
    [cDNA] MGC:55809 (1), MGC:152957 (1), MGC:191585 (1)
    srsf4 Has Artifact: [cDNA] MGC:86853
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199574 (1) 1845 nt
    Genomic GenBank:CR450687 (1) 143150 nt
    Select Tool
    Polypeptide UniProtKB:Q802Y1 (1) 366 aa
    Sequence Information (all 25)
    ORTHOLOGY for srsf4 ( Chr: 19 )
    CITATIONS (26)