ZFIN ID: ZDB-GENE-030131-5889
Gene Name: nudE neurodevelopment protein 1-like 1b
Gene Symbol: ndel1b    Nomenclature History

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Previous Names: wu:fi23c04, wu:fi23e06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have microtubule binding activity. Predicted to be involved in several processes, including centrosome localization; microtubule cytoskeleton organization; and vesicle transport along microtubule. Predicted to localize to centrosome; kinesin complex; and kinetochore. Is expressed in brain; hindbrain neural plate; notochord; somite; and trunk. Orthologous to human NDEL1 (nudE neurodevelopment protein 1 like 1).
Genome Resources: Alliance (1),  Gene:333957 (1),  Ensembl(GRCz11):ENSDARG00000104225 (1)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 5 figures (5 images) from Thisse et al., 2004 [MGC:55384]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31358 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ndel1b
    2
    CRISPR2-ndel1b
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ndel1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ndel1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitotic centrosome separation (more)
    Cellular Component cytoplasm (more)
    Molecular Function microtubule binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ndel1b-201 (1)    Ensembl 3598
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ndel1b No data available
    MARKER RELATIONSHIPS
    ndel1b Contained in: [BAC] DKEY-217L10 (1) (order this)
    ndel1b Contains: [SNP] rs3727732 (1), rs3727733 (1), rs3727734 (1)
    ndel1b Encodes: [EST] fi23c04, fi23e06
    [cDNA] MGC:55384 (1), MGC:193101 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201307 (1) 3899 nt
    Genomic GenBank:BX682555 (1) 69193 nt
    Select Tool
    Polypeptide UniProtKB:A5JEM5 (1) 344 aa
    Sequence Information (all 21)
    ORTHOLOGY for ndel1b ( Chr: 3 )
    CITATIONS (30)