ZFIN ID: ZDB-GENE-030131-5861
Gene Name: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
Gene Symbol: gnai2b    Nomenclature History

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Previous Names: gnai2, fi21e06, Galpha i2a (1), wu:fi21e06, zgc:56690

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in G protein-coupled adenosine receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and gamma-aminobutyric acid signaling pathway. Predicted to localize to heterotrimeric G-protein complex. Is expressed in several structures, including barbel; lip; nervous system; neural tube; and tail bud. Orthologous to human GNAI2 (G protein subunit alpha i2).
Genome Resources: Alliance (1),  Gene:327650 (1),  Ensembl(GRCz11):ENSDARG00000017294 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025666Tg Transgenic Insertion Unknown Unknown DNA
sa33974 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33975 Point Mutation Unknown Missense, Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gnai2b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Pituitary adenoma, ACTH-secreting, somatic
    Ventricular tachycardia, idiopathic 192605
    DISEASE ASSOCIATED WITH gnai2b VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gnai2b-202 (1)    Ensembl 2618
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gnai2b No data available
    MARKER RELATIONSHIPS
    gnai2b Contained in: [BAC] CH73-62L15 (1), CH73-341P16 (1)
    gnai2b Encodes: [EST] fi21e06
    [cDNA] MGC:56690 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199842 (1) 1976 nt
    Genomic GenBank:CU468828 (1) 88142 nt
    Select Tool
    Polypeptide UniProtKB:X1WDQ5 (1) 355 aa
    Sequence Information (all 12)
    ORTHOLOGY for gnai2b ( Chr: 6 )
    CITATIONS (33)