Gene

cdc42ep5

ID
ZDB-GENE-030131-5813
Name
CDC42 effector protein (Rho GTPase binding) 5
Symbol
cdc42ep5 Nomenclature History
Previous Names
  • cdc42ep1
  • cdc42ep1b
  • wu:fi19g04
  • zgc:153966
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have GTP-Rho binding activity. Predicted to be involved in Rho protein signal transduction; positive regulation of cellular component biogenesis; and regulation of cell shape. Predicted to localize to cytoplasm; cytoskeleton; and plasma membrane. Is expressed in artery; cardiovascular system; notochord; pharyngeal arch; and polster. Orthologous to human CDC42EP5 (CDC42 effector protein 5).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdc42ep5 Human Ortholog
No data available
Associated With cdc42ep5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000095 CRIB domain
Family IPR029273 Cdc42 effector
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Orthology Note
Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be cdc42ep1b based on amino acid similarity to human CDC42EP1. Subsequent analysis suggests it is the ortholog of human CDC42EP5 and mouse Cdc42ep5 based on amino acid similarity and conserved synteny.
Citations