Gene

alg8

ID
ZDB-GENE-030131-5812
Name
ALG8 alpha-1,3-glucosyltransferase
Symbol
alg8 Nomenclature History
Previous Names
  • si:rp71-1p14.2
  • wu:fi19e09
  • wu:fi19f07 (1)
  • zgc:112507
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ih and polycystic liver disease. Orthologous to human ALG8 (ALG8 alpha-1,3-glucosyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alg8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital disorder of glycosylation Ih Alliance Congenital disorder of glycosylation, type Ih 608104
Polycystic liver disease 3 with or without kidney cysts 617874
Associated With alg8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004856 Glycosyl transferase, ALG6/ALG8
Domain Details Per Protein
Protein Length Glycosyl transferase, ALG6/ALG8
UniProtKB:Q566T2 524
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations