ZFIN ID: ZDB-GENE-030131-5788
Gene Name: DIRAS family, GTP-binding RAS-like 1a
Gene Symbol: diras1a    Nomenclature History

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Previous Names: diras1, fi18d11, wu:fi18d11, zgc:55360 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have GDP binding activity; GTP binding activity; and GTPase activity. Involved in neuron development and trigeminal ganglion development. Predicted to localize to plasma membrane. Is expressed in nervous system and otic vesicle. Orthologous to human DIRAS1 (DIRAS family GTPase 1).
Genome Resources: Alliance (1),  Gene:327577 (1),  Ensembl(GRCz11):ENSDARG00000028066 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5591 Point Mutation Unknown Splice Site ENU
sa35021 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-diras1a N/A 1
    MO2-diras1a N/A 1
    DISEASE ASSOCIATED WITH diras1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH diras1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuron development (more)
    Cellular Component membrane (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA diras1a-201 (1)    Ensembl 2475
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM diras1a No data available
    MARKER RELATIONSHIPS
    diras1a Contained in: [BAC] DKEY-197I20 (1) (order this)
    diras1a Encodes: [EST] fi18d11
    [cDNA] MGC:55360 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199831 (1) 2142 nt
    Genomic GenBank:CR678040 (1) 119986 nt
    Select Tool
    Polypeptide UniProtKB:F1QSQ6 (1) 195 aa
    Sequence Information (all 12)
    ORTHOLOGY for diras1a ( Chr: 11 )
    CITATIONS (23)