Gene

kif14

ID
ZDB-GENE-030131-5759
Name
kinesin family member 14
Symbol
kif14 Nomenclature History
Previous Names
  • si:dkey-39e8.3
  • wu:fi16h07
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to localize to kinesin complex and microtubule. Human ortholog(s) of this gene implicated in Meckel syndrome and primary autosomal recessive microcephaly. Orthologous to human KIF14 (kinesin family member 14).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Reilly et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kif14 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Microcephaly 20, primary, autosomal recessive 617914
?Meckel syndrome 12 616258
Associated With kif14 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019821 Kinesin motor domain, conserved site
Domain IPR000253 Forkhead-associated (FHA) domain
Domain IPR001752 Kinesin motor domain
Domain IPR032405 Kinesin-associated
Family IPR027640 Kinesin-like protein
Homologous_superfamily IPR008984 SMAD/FHA domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Forkhead-associated (FHA) domain Kinesin-associated Kinesin-like protein Kinesin motor domain Kinesin motor domain, conserved site Kinesin motor domain superfamily P-loop containing nucleoside triphosphate hydrolase SMAD/FHA domain superfamily
UniProtKB:F1Q554 1506
UniProtKB:A0A2R8QTR7 1491
UniProtKB:Q1LW14 1307
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations