Gene

arid1ab

ID
ZDB-GENE-030131-5725
Name
AT rich interactive domain 1Ab (SWI-like)
Symbol
arid1ab Nomenclature History
Previous Names
  • fb82h08
  • fi15b05
  • im:7160733
  • si:dkey-180c19.1
  • wu:fb82h08
  • wu:fi15b05
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Predicted to be involved in ATP-dependent chromatin remodeling; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of SWI/SNF complex and nBAF complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 2; breast cancer; carcinoma (multiple); gastrointestinal system cancer (multiple); and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arid1ab Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Coffin-Siris syndrome 2 Alliance Coffin-Siris syndrome 2 614607
Associated With arid1ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001606 ARID DNA-binding domain
Domain IPR033388 SWI/SNF-like complex subunit BAF250, C-terminal
Family IPR021906 SWI/SNF-like complex subunit BAF250/Osa
Family IPR030094 SWI/SNF-like complex subunit BAF250a
Homologous_superfamily IPR036431 ARID DNA-binding domain superfamily
Domain Details Per Protein
Protein Length ARID DNA-binding domain ARID DNA-binding domain superfamily SWI/SNF-like complex subunit BAF250a SWI/SNF-like complex subunit BAF250, C-terminal SWI/SNF-like complex subunit BAF250/Osa
UniProtKB:A0A0R4IR17 2101
UniProtKB:A0A2R8QFG7 2190
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations