ZFIN ID: ZDB-GENE-030131-5717
Gene Name: creatine kinase, mitochondrial 2a (sarcomeric)
Gene Symbol: ckmt2a    Nomenclature History

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Previous Names: fi14g08, wu:fi14g08, zgc:56085 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and kinase activity. Predicted to be involved in phosphorylation. Is expressed in myotome and retina. Orthologous to human CKMT2 (creatine kinase, mitochondrial 2).
Genome Resources: Alliance (1),  Gene:327506 (1),  Ensembl(GRCz11):ENSDARG00000069615 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Directly Submitted Expression Data: 4 figures (7 images) from Thisse et al., 2004 [MGC:56085]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31761 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38771 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ckmt2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ckmt2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphocreatine biosynthetic process (more)
    Cellular Component mitochondrion (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Active_site IPR022415 ATP:guanido phosphotransferase active site
    Domain IPR022413 ATP:guanido phosphotransferase, N-terminal
    Domain IPR022414 ATP:guanido phosphotransferase, catalytic domain
    Family IPR000749 ATP:guanido phosphotransferase
    Homologous_superfamily IPR014746 Glutamine synthetase/guanido kinase, catalytic domain
    Homologous_superfamily IPR036802 ATP:guanido phosphotransferase, N-terminal domain superfamily
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ckmt2a No data available
    MARKER RELATIONSHIPS
    ckmt2a Encodes: [EST] fi14g08
    [cDNA] MGC:56085 (1), MGC:192048 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199816 (1) 1349 nt
    Polypeptide UniProtKB:A0A0R4IFJ7 (1) 417 aa
    Sequence Information (all 25)
    ORTHOLOGY for ckmt2a ( Chr: 10 )
    CITATIONS (23)