ZFIN ID: ZDB-GENE-030131-5677
Gene Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
Gene Symbol: dyrk1ab    Nomenclature History

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Previous Names: fi12h09, wu:fi12h09, wu:fi26g04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity and transcription coactivator activity. Predicted to be involved in peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in endothelial cell; heart; and nervous system.
Genome Resources: Alliance (1),  Gene:327466 (1),  Ensembl(GRCz11):ENSDARG00000023814 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012687Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019205Tg Transgenic Insertion Unknown Unknown DNA
    sa9999 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28438 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dyrk1ab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dyrk1ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dyrk1ab-201 (1)    Ensembl 5881
    dyrk1ab-202 (1)    Ensembl 518
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dyrk1ab No data available
    MARKER RELATIONSHIPS
    dyrk1ab Contained in: [BAC] CH211-229D2 (1)
    dyrk1ab Encodes: [EST] fi12h09, fi26g04
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001347831 (1)
    Genomic GenBank:CR848759 (1) 167536 nt
    Select Tool
    Polypeptide UniProtKB:F1Q693 (1) 727 aa
    Sequence Information (all 18)
    ORTHOLOGY for dyrk1ab ( Chr: 15 )
    CITATIONS (20)