Gene

dyrk1ab

ID
ZDB-GENE-030131-5677
Name
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
Symbol
dyrk1ab Nomenclature History
Previous Names
  • fi12h09
  • wu:fi12h09
  • wu:fi26g04
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity and transcription coactivator activity. Predicted to be involved in peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in endothelial cell; heart; and nervous system.
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Cho et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dyrk1ab Human Ortholog
No data available
Associated With dyrk1ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR044131 Dual specificity tyrosine-phosphorylation-regulated kinase 1A/1B, catalytic domain
Family IPR028318 Dual specificity tyrosine-phosphorylation-regulated kinase 1A/B
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Dual specificity tyrosine-phosphorylation-regulated kinase 1A/1B, catalytic domain Dual specificity tyrosine-phosphorylation-regulated kinase 1A/B Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:R4GE54 113
UniProtKB:A9QVW5 395
UniProtKB:X1WCB7 719
UniProtKB:F1Q693 727
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations