ZFIN ID: ZDB-GENE-030131-5651
Gene Name: nucleolus and neural progenitor protein
Gene Symbol: nepro    Nomenclature History

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Previous Names: fi11c01, si:dkey-22a1.3, wu:fi11c01, zgc:112065 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to be involved in negative regulation of neuron differentiation and positive regulation of Notch signaling pathway. Predicted to localize to the nucleolus. Orthologous to human NEPRO (nucleolus and neural progenitor protein).
Genome Resources: Alliance (1),  Gene:550343 (1),  Ensembl(GRCz11):ENSDARG00000043566 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:112065]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41431 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nepro HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nepro VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of neuron differentiation (more)
    Cellular Component nucleolus (more)
    Molecular Function molecular_function (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR027951 Domain of unknown function DUF4477
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nepro-202 (1)    Ensembl 1879
    ncRNA si:dkey-22a1.3-002 (1)    Ensembl 867
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nepro No data available
    MARKER RELATIONSHIPS
    nepro Contained in: [BAC] DKEY-22A1 (1) (order this), DKEY-193N17 (1) (order this)
    nepro Encodes: [EST] fi11c01
    [cDNA] MGC:112065 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001017650 (1) 1693 nt
    Genomic GenBank:BX322637 178563 nt
    Select Tool
    Polypeptide UniProtKB:F1QA51 (1) 536 aa
    Sequence Information (all 18)
    ORTHOLOGY for nepro ( Chr: 9 )
    CITATIONS (20)