ZFIN ID: ZDB-GENE-030131-5648
Gene Name: jade family PHD finger 1
Gene Symbol: jade1    Nomenclature History

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Previous Names: fi11a04, phf17, wu:fi11a04, zgc:55323

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Involved in regulation of canonical Wnt signaling pathway. Predicted to localize to cytoplasm and nucleus. Orthologous to human JADE1 (jade family PHD finger 1).
Genome Resources: Alliance (1),  Gene:327437 (1),  Ensembl(GRCz11):ENSDARG00000033707 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55323]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1499 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10070 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10671 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45609 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-jade1
    1
    CRISPR2-jade1
    1
    MO1-jade1 N/A 1
    MO2-jade1 N/A 1
    MO3-jade1 N/A 1
    PHENOTYPE
    Data: Fig. 6 from Borgal et al., 2012
    Observed in:
    DISEASE ASSOCIATED WITH jade1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH jade1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of canonical Wnt signaling pathway (more)
    Cellular Component cell projection (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA jade1-201 (1)    Ensembl 3842
    ncRNA jade1-002 (1)    Ensembl 539
    jade1-003 (1)    Ensembl 796
    jade1-004 (1)    Ensembl 736
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM jade1 No data available
    MARKER RELATIONSHIPS
    jade1 Contained in: [BAC] DKEY-221L4 (1) (order this)
    jade1 Encodes: [EST] fi11a04
    [cDNA] MGC:55323 (1), MGC:192761 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199805 (1) 3172 nt
    Genomic GenBank:AL928908 (1) 229790 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B2GSW7 (1) 829 aa
    Sequence Information (all 25)
    ORTHOLOGY for jade1 ( Chr: 17 )
    CITATIONS (28)