ZFIN ID: ZDB-GENE-030131-5607
Gene Name: Ras-related associated with diabetes
Gene Symbol: rrad    Nomenclature History

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Previous Names: fi06a10, wu:fi06a10, zgc:63471

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity and signal transduction. Predicted to localize to plasma membrane. Is expressed in cardiovascular system; endocrine system; nervous system; and otic vesicle. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator).
Genome Resources: Alliance (1),  Gene:327396 (1),  Ensembl(GRCz11):ENSDARG00000052011 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1939 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rrad HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rrad VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of high voltage-gated calcium channel activity (more)
    Cellular Component membrane (more)
    Molecular Function calcium channel regulator activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rrad-201 (1)    Ensembl 1747
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rrad No data available
    MARKER RELATIONSHIPS
    rrad Contained in: [BAC] CH211-235L10 (1)
    rrad Encodes: [EST] fi06a10
    [cDNA] MGC:63471 (1), MGC:174042 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199798 (1) 1778 nt
    Genomic GenBank:BX511110 (1) 89482 nt
    Select Tool
    Polypeptide UniProtKB:A8E566 (1) 300 aa
    Sequence Information (all 21)
    ORTHOLOGY for rrad ( Chr: 7 )
    CITATIONS (23)