ZFIN ID: ZDB-GENE-030131-5584
Gene Name: karyopherin alpha 4 (importin alpha 3)
Gene Symbol: kpna4    Nomenclature History

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Previous Names: wu:fa56d07, wu:fa66g10, wu:fe14c04, wu:fi04h11, wu:fi19b05

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to localize to nucleoplasm. Orthologous to human KPNA4 (karyopherin subunit alpha 4).
Genome Resources: Alliance (1),  Gene:327373 (1),  Ensembl(GRCz11):ENSDARG00000023190 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55488]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30680 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32009 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH kpna4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH kpna4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein import into nucleus (more)
    Cellular Component cytoplasm (more)
    Molecular Function nuclear import signal receptor activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA kpna4-201 (1)    Ensembl 3496
    kpna4-202 (1)    Ensembl 735
    ncRNA kpna4-003 (1)    Ensembl 780
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kpna4 No data available
    MARKER RELATIONSHIPS
    kpna4 Contained in: [BAC] CH211-196B13 (1)
    kpna4 Encodes: [EST] fa56d07 (1), fa66g10 (1), fe14c04 (1), fi04h11, fi19b05 (1)
    [cDNA] MGC:55488 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201305 (1) 3510 nt
    Genomic GenBank:CR478286 (1) 188644 nt
    Select Tool
    Polypeptide UniProtKB:Q6PUQ6 (1) 531 aa
    Sequence Information (all 22)
    ORTHOLOGY for kpna4 ( Chr: 15 )
    CITATIONS (24)