ZFIN ID: ZDB-GENE-030131-5512
Gene Name: protein phosphatase 1, catalytic subunit, alpha isozyme b
Gene Symbol: ppp1cab    Nomenclature History

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Previous Names: fb18b03, fd20h04, wu:fb18b03, wu:fd20h04, wu:fl22a03, zgc:76940

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine phosphatase activity. Involved in angiogenesis. Predicted to localize to cytoplasm and nucleus. Is expressed in female organism. Orthologous to human PPP1CA (protein phosphatase 1 catalytic subunit alpha).
Genome Resources: Alliance (1),  Gene:327301 (1),  Ensembl(GRCz11):ENSDARG00000071566 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55744]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012110Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27914 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ppp1cab N/A 1
    MO2-ppp1cab N/A 1
    TALEN1-ppp1cab
    1
    DISEASE ASSOCIATED WITH ppp1cab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp1cab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component cytoplasm (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp1cab-201 (1)    Ensembl 2233
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp1cab No data available
    MARKER RELATIONSHIPS
    ppp1cab Contained in: [BAC] CH211-125G7 (1)
    ppp1cab Encodes: [EST] fb18b03, fd20h04, fl22a03 (1)
    [cDNA] MGC:55744 (1), MGC:76940 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212710 (1) 2263 nt
    Genomic GenBank:CT954256 (1) 101610 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZVR3 (1) 332 aa
    Sequence Information (all 20)
    ORTHOLOGY for ppp1cab ( Chr: 12 )
    CITATIONS (30)