ZFIN ID: ZDB-GENE-030131-5493
Gene Name: protein disulfide isomerase family A, member 4
Gene Symbol: pdia4    Nomenclature History

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Previous Names: cai (1), fj23a12, wu:fd20c07, wu:fj23a12, zgc:113965, zgc:136625, zgc:77773

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have protein disulfide isomerase activity. Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to localize to cell surface and endoplasmic reticulum. Orthologous to human PDIA4 (protein disulfide isomerase family A member 4).
Genome Resources: Alliance (1),  Gene:554998 (1),  Ensembl(GRCz11):ENSDARG00000018491 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [IMAGE:7148716]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13170 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37857 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44116 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdia4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pdia4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell redox homeostasis (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function isomerase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pdia4-201 (1)    Ensembl 2399
    ncRNA pdia4-002 (1)    Ensembl 777
    pdia4-003 (1)    Ensembl 850
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdia4 No data available
    MARKER RELATIONSHIPS
    pdia4 Contained in: [BAC] DKEY-117J14 (order this)
    pdia4 Encodes: [EST] fd20c07, fj23a12, IMAGE:7148716 (1)
    [cDNA] MGC:56014 (1), MGC:77773 (1), MGC:113965 (1), MGC:136625 (1), MGC:192721 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199779 (1) 2342 nt
    Genomic GenBank:BX005392 (1) 178765 nt
    Select Tool
    Polypeptide UniProtKB:Q6P3I1 (1) 645 aa
    Sequence Information (all 29)
    ORTHOLOGY for pdia4 ( Chr: 24 )
    CITATIONS (32)