ZFIN ID: ZDB-GENE-030131-5474
Gene Name: protein phosphatase 2, regulatory subunit B, alpha b
Gene Symbol: ppp2r2ab    Nomenclature History

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Previous Names: MDS026 (1), ppp2r2a, ppp2r2d, wu:fd19g04, zgc:63780

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to contribute to protein serine/threonine phosphatase activity. Involved in blood vessel lumenization. Predicted to localize to the cytosol and protein phosphatase type 2A complex. Orthologous to human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha).
Genome Resources: Alliance (1),  Gene:327263 (1),  Ensembl(GRCz11):ENSDARG00000006624 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7144038]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017423Tg Transgenic Insertion Unknown Unknown DNA
sa10037 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ppp2r2ab N/A 2
    MO2-ppp2r2ab N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ppp2r2ab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp2r2ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel lumenization (more)
    Cellular Component protein phosphatase type 2A complex (more)
    Molecular Function protein phosphatase regulator activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000009 Protein phosphatase 2A regulatory subunit PR55
    Repeat IPR001680 WD40 repeat
    Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Conserved_site IPR018067 Protein phosphatase 2A regulatory subunit PR55, conserved site
    Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp2r2ab-202 (1)    Ensembl 2199
    ncRNA ppp2r2ab-002 (1) 566
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp2r2ab No data available
    MARKER RELATIONSHIPS
    ppp2r2ab Contained in: [BAC] CH211-46G6 (1), CH211-217K11 (1)
    ppp2r2ab Encodes: [EST] fd19g04, IMAGE:7144038 (1)
    [cDNA] MGC:63780 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199776 (1) 2002 bp
    Genomic GenBank:AL928714 (1) 170509 bp
    Select Tool
    Polypeptide UniProtKB:A2BG80 (1) 448 aa
    Sequence Information (all 16)
    ORTHOLOGY for ppp2r2ab ( Chr: 10 )
    CITATIONS (29)