Gene

ofd1

ID
ZDB-GENE-030131-5427
Name
OFD1 centriole and centriolar satellite protein
Symbol
ofd1 Nomenclature History
Previous Names
  • wu:fa07a10
  • wu:fd17e11
  • zgc:92562
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Involved in convergent extension involved in gastrulation; determination of heart left/right asymmetry; and epithelial cilium movement involved in determination of left/right asymmetry. Localizes to centrosome; ciliary basal body; and nucleus. Is expressed in Kupffer's vesicle; lateral line primordium; neuromast; and otic vesicle. Human ortholog(s) of this gene implicated in Joubert syndrome 10; Simpson-Golabi-Behmel syndrome type 2; orofaciodigital syndrome I; retinitis pigmentosa; and retinitis pigmentosa 23. Orthologous to human OFD1 (OFD1 centriole and centriolar satellite protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ofd1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Joubert syndrome 10 Alliance Joubert syndrome 10 300804
orofaciodigital syndrome I Alliance Orofaciodigital syndrome I 311200
retinitis pigmentosa 23 Alliance ?Retinitis pigmentosa 23 300424
Simpson-Golabi-Behmel syndrome type 2 Alliance Simpson-Golabi-Behmel syndrome, type 2 300209
Associated With ofd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006594 LIS1 homology motif
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations