ZFIN ID: ZDB-GENE-030131-5426
Gene Name: cullin 5a
Gene Symbol: cul5a    Nomenclature History

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Previous Names: cul5, wu:fd17d09, wu:fi20h12, xx:11fd17d09, zgc:66185

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to localize to Cul5-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Orthologous to human CUL5 (cullin 5).
Genome Resources: Alliance (1),  Gene:327215 (1),  Ensembl(GRCz11):ENSDARG00000069742 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66185]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019173Tg Transgenic Insertion Unknown Unknown DNA
sa22609 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42514 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cul5a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cul5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ubiquitin-dependent protein catabolic process (more)
    Cellular Component cullin-RING ubiquitin ligase complex (more)
    Molecular Function ubiquitin protein ligase binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cul5a-201 (1)    Ensembl 2713
    Browsers: UCSCEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cul5a No data available
    MARKER RELATIONSHIPS
    cul5a Contained in: [BAC] CH211-24O10 (1)
    cul5a Encodes: [EST] fd17d09, fi20h12 (1)
    [cDNA] MGC:66185 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212706 (1) 3546 nt
    Genomic GenBank:BX572630 (1) 174316 nt
    Select Tool
    Polypeptide UniProtKB:F1REN0 (1) 780 aa
    Sequence Information (all 15)
    ORTHOLOGY for cul5a ( Chr: 15 )
    CITATIONS (23)